The green Knoevenagel condensation: solvent-free condensation of benzaldehydes
نویسندگان
چکیده
منابع مشابه
Base-free Knoevenagel condensation catalyzed by copper metal surfaces.
For the first time Knoevenagel condensation has been catalyzed by elemental copper with unexpected activity and excellent isolated yields. Inexpensive, widely available copper powder was used to catalyze the condensation of cyanoacetate and benzaldehyde under mild conditions. To ensure general applicability, a wide variety of different substrates was successfully reacted.
متن کاملMechanochemical Knoevenagel condensation investigated in situ
The mechanochemical Knoevenagel condensation of malononitrile with p-nitrobenzaldehyde was studied in situ using a tandem approach. X-ray diffraction and Raman spectroscopy were combined to yield time-resolved information on the milling process. Under solvent-free conditions, the reaction leads to a quantitative conversion to p-nitrobenzylidenemalononitrile within 50 minutes. The in situ data i...
متن کاملSynthesis of substituted stilbenes via the Knoevenagel condensation.
Knoevenagel condensations between aldehydes and substrates containing active methylene groups were carried out in ethanol at room temperature, in the presence of potassium phosphate, to afford unsymmetrical olefins. These condensations have been shown to afford only the E-isomers in greater than 80% yields. Salicylaldehyde first produces the Knoevenagel condensation products, which undergo a su...
متن کاملBaO/TiO2-ZrO2 as a green and efficient basic catalyst for Knoevenagel condensation reaction
A simple and green synthetic strategy to prepare BaO/TiO2-ZrO2 as a solid base catalyst was reported. These materials with various amounts of BaO were prepared by the adsorption method. The physical and chemical properties of BaO/TiO2-ZrO2 were investigated by X-ray diffraction, X-ray fluorescence, specific surface area and BJH pore size distribution, FT-IR spectroscopy, scanning electron micro...
متن کاملMicrowave-assisted and efficient solvent-free knoevenagel condensation. A sustainable protocol using porous calcium hydroxyapatite as catalyst.
A sustainable Knoevenagel condensation of a series of aldehydes with malononitrile and ethyl cyanoacetate is described. The process is based on the combination of microwave activation and hydroxyapatite catalysis under solvent-free conditions. Products are obtained in and high yields after short reaction times. The effects of the specific surface of porous calcium hydroxyapatite and microwave a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Green Chemistry Letters and Reviews
سال: 2017
ISSN: 1751-8253,1751-7192
DOI: 10.1080/17518253.2017.1391881